The Urinary Stone Disease Research Network (USDRN) is a group of scientists and investigators designing and conducting research on urinary stones (kidney stones) in adults and children in order to learn more about

  • who forms kidney stones,
  • what are the best treatments,
  • how to prevent stones from forming.

Funded by the National Institutes of Health (NIH) and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the network comprises a wide range of experts including adult and pediatric urologists, adult and pediatric nephrologists (kidney specialists), pediatricians, emergency department physicians, clinical trialists, nutritionists, behavioral scientists, and radiologists.

The Duke Clinical Research Institute is the USDRN Scientific Data Research Center and four clinical sites are conducting the studies:

  • University of Pennsylvania/Children's Hospital of Philadelphia
  • University of Texas Southwestern Medical Center
  • University of Washington
  • Washington University in St. Louis

The coordinating center and clinical sites work together in planning, executing, and analyzing the results from USDRN studies.


USDRN Studies Tackle Urinary Stone Disease to Improve Health Outcomes

DURHAM, N.C. (March 1, 2020)—Through new enrollment strategies and collaborative partnerships, USDRN researchers aim to improve patient care and experience for individuals with urinary stone disease and ureteral stents. Download the press release below to learn how the Prevention of Urinary Stones with Hydration (PUSH) and the Study to Enhance uNderstanding of sTent-associated Symptoms (STENTS) studies are reaching a broader population to improve health outcomes.


Direct charges infographic
Prevalence has almost doubled and we don't know why from 1994 to 2007 it went from 5 to 10 percent


Since 1994, the number of people who get kidney stones has almost doubled! The number has risen from 1 out of every 20 people, to now 1 out of every 11 people. This increase is likely due to diet and lifestyle factors. Obesity also increases the risk of having a kidney stone.

Kidney stones are more common in men than women, while less common in people who are Hispanic and African-American.

Infographic of incidence

of people who have a kidney ston 31 percent will have another stone within the next 10 years