Dr. John C. Leiske

Professor of Medicine
Division of Nephrology and Hypertension
Mayo Clinic, Rochester, MN

---

Dr. Lieske is a nephrologist with a long-standing interest in the pathogenesis and treatment of urinary stone disease. Dr. Lieske is also medical director of the Renal Testing Laboratory in the Mayo Clinic Department of Laboratory Medicine that performs all kidney related testing including those related to the diagnosis and treatment of kidney stone patients. Over the last decade he has completed clinical trials evaluating the effect of diet, probiotics, phosphate binders, vasopressin antagonism, and small inhibitory RNA in stone disease patients with and without primary or enteric hyperoxaluria. Dr. Lieske also studies the genetics of monogenic and common kidney stones as well as the role of intrarenal macrophages/inflammation in urinary stone pathogenesis, and is director of the Rare Kidney Stone Consortium.